Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 15/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132711 | 0.81 | FDPS (0.44) | LMNAFDPSPGK1PGK2GGPS1 | |
| SCHEMBL20143680 | 0.76 | LMNA (0.36) | LMNAFDPS | |
| SCHEMBL4183139 | 0.76 | LMNA (0.43) | LMNAFDPSPGK1PGK2GGPS1 | |
| SCHEMBL5463500 | 0.69 | LMNA (0.47) | LMNAFDPSPGK1PGK2GGPS1 | |
| SCHEMBL2384958 | 0.69 | LMNA (0.56) | LMNAFDPSPGK1PGK2GGPS1 | |
| SCHEMBL11881792 | 0.67 | LMNA (0.50) | LMNAFDPSPGK1PGK2GGPS1 | |
| SCHEMBL5606672 | 0.67 | LMNA (0.53) | LMNAFDPSPGK1PGK2GGPS1 | |
| SCHEMBL16342196 | 0.67 | LMNA (0.35) | LMNAFDPSGGPS1 | |
| SCHEMBL18873441 | 0.67 | FDPS (0.44) | LMNAFDPSPGK1PGK2GGPS1 | |
| SCHEMBL14853006 | 0.67 | LMNA (0.39) | LMNAFDPSPGK1PGK2GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150103639-A1 | COATING OF SURFACES INTENDED FOR HOROLOGY BY USING CATANIONIC COMPOSITIONS CONTAINING PHOSPHONIC MOLECULES AND AMINES | ASSOCIATION SUISSE POUR LA RECHERCHE HORLOGERE (CH) | 2015-04-16 | — | — | US | disclosed |