SCHEMBL16639289

SCHEMBL16639289

c1ccc(-c2ccccc2N(c2ccc(-c3ccc4ccc5c(-c6ccc(N(c7ccccc7-c7ccccc7)c7cccc8c7sc7ccccc78)cc6)ccc6ccc3c4c65)cc2)c2cccc3c2sc2ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F9 P00740 1/20 0.38
ALOX5 P09917 1/20 0.38
SLC9A1 P19634 1/20 0.32
PARP14 Q460N5 1/20 0.31
LIMK1 P53667 1/20 0.31
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16639314 0.94 F9 (0.36) F9ALOX5SLC9A1
SCHEMBL16639313 0.92 F9 (0.35) F9ALOX5SLC9A1TNKSTNKS2
SCHEMBL26262989 0.89 F9 (0.35) F9ALOX5SLC9A1PARP14LIMK1
SCHEMBL22155362 0.88 ALOX5 (0.44) F9ALOX5SLC9A1PARP14LIMK1
SCHEMBL21206177 0.88 ALOX5 (0.43) F9ALOX5SLC9A1PARP14LIMK1
SCHEMBL21214776 0.88 ALOX5 (0.46) F9ALOX5SLC9A1PARP14LIMK1
SCHEMBL24889449 0.88 ALOX5 (0.38) F9ALOX5SLC9A1PARP14LIMK1
SCHEMBL21096898 0.87 ALOX5 (0.41) F9ALOX5SLC9A1PARP14LIMK1
SCHEMBL24889782 0.86 ALOX5 (0.39) F9ALOX5SLC9A1PARP14LIMK1
SCHEMBL22255465 0.86 ALOX5 (0.41) F9ALOX5SLC9A1PARP14LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed