SCHEMBL22155362

SCHEMBL22155362

c1ccc(-c2ccc(-c3ccc(N(c4ccccc4-c4ccccc4)c4cccc5c4sc4ccccc45)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
F9 P00740 1/20 0.38
PARP14 Q460N5 1/20 0.36
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
GPR3 P46089 1/20 0.34
LIMK1 P53667 3/20 0.33
SLC9A1 P19634 1/20 0.32
PRKDC P78527 2/20 0.32
PIM3 Q86V86 1/20 0.30
PTPN1 P18031 1/20 0.30
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24472257 0.96 ALOX5 (0.45) ALOX5F9PARP14TNKSTNKS2
SCHEMBL21168545 0.96 ALOX5 (0.45) ALOX5F9PARP14TNKSTNKS2
SCHEMBL18212087 0.95 ALOX5 (0.50) ALOX5F9PARP14TNKSTNKS2
SCHEMBL24472470 0.95 ALOX5 (0.44) ALOX5F9PARP14TNKSTNKS2
SCHEMBL21214776 0.94 ALOX5 (0.46) ALOX5F9PARP14TNKSTNKS2
SCHEMBL24370265 0.93 ALOX5 (0.43) ALOX5F9PARP14TNKSTNKS2
SCHEMBL24370078 0.93 ALOX5 (0.43) ALOX5F9PARP14TNKSTNKS2
SCHEMBL15964352 0.93 ALOX5 (0.42) ALOX5F9PARP14TNKSTNKS2
SCHEMBL15964350 0.93 ALOX5 (0.42) ALOX5F9PARP14TNKSTNKS2
SCHEMBL22255465 0.93 ALOX5 (0.41) ALOX5F9PARP14TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172060-A1 ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO LTD (KR) 2023-06-01 US disclosed
US-20230172060-A1 ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO LTD (KR) 2023-06-01 US disclosed
US-20200203619-A1 ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO., LTD. (KR) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200203619-A1 ORGANIC LIGHT EMITTING DEVICE MAP1LC3A, MAP1LC3C, MAP1LC3B ALOX5 1081/4885F9 3650/4885PARP14 1146/4885
US-20230172060-A1 ORGANIC LIGHT EMITTING DEVICE MAP1LC3A, MAP1LC3C, MAP1LC3B ALOX5 1081/4885F9 3650/4885PARP14 1146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.