SCHEMBL16639298

SCHEMBL16639298

Cc1ccc(N(c2ccc(-c3ccc4ccc5c(N(c6ccccc6)c6ccc7oc8ccccc8c7c6)ccc6ccc3c4c65)cc2)c2ccc(-c3ccccc3)cc2-c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.33
TNKS O95271 1/20 0.31
PARP1 P09874 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
PARP2 Q9UGN5 1/20 0.31
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16639638 0.95 PGR (0.33) PGR
SCHEMBL16639303 0.94 MAOB (0.33) MAOBTNKSPARP1TNKS2PARP2
SCHEMBL16639291 0.92 PGR (0.34) MAOBPGR
SCHEMBL16639339 0.90 PGR (0.30) PGR
SCHEMBL16639297 0.90 PGR (0.33) PGR
SCHEMBL16639324 0.89 KDM4E (0.31)
SCHEMBL16639325 0.89 MAOB (0.31) MAOB
SCHEMBL21515766 0.87 MAOB (0.36) MAOBTNKSPARP1TNKS2PARP2
SCHEMBL16639280 0.85 HPRT1 (0.37) MAOB
SCHEMBL21515717 0.85 MAOB (0.37) MAOBTNKSPARP1TNKS2PARP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed