Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639324 | 0.95 | KDM4E (0.31) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL16639339 | 0.94 | PGR (0.30) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL16639298 | 0.94 | MAOB (0.33) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL16639288 | 0.91 | KDM4E (0.33) | MAOBTNKSKDM4EALDH1A1MAPT | |
| SCHEMBL16639297 | 0.89 | PGR (0.33) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL16639638 | 0.89 | PGR (0.33) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL21515766 | 0.88 | MAOB (0.36) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL16639337 | 0.88 | ALOX5 (0.32) | MAOB | |
| SCHEMBL26687150 | 0.86 | NPC1 (0.35) | TNKSPARP1TNKS2TP53KDM4E | |
| SCHEMBL21515717 | 0.86 | MAOB (0.37) | MAOBTNKSPARP1TNKS2PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |
| US-20150102290-A1 | DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP | UNIVERSAL DISPLAY CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |