Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639293 | 0.95 | TDP1 (0.39) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL16639634 | 0.92 | RXRA (0.31) | L3MBTL1MAPTSMN1; SMN2RXRARXRB | |
| SCHEMBL16639338 | 0.92 | RXRA (0.31) | L3MBTL1MAPTSMN1; SMN2RXRARXRB | |
| SCHEMBL16641952 | 0.92 | RXRA (0.31) | L3MBTL1MAPTSMN1; SMN2RXRARXRB | |
| SCHEMBL16639282 | 0.91 | CRHR1 (0.33) | ALDH1A1HPGDTDP1L3MBTL1KDM4E | |
| SCHEMBL16639285 | 0.90 | CRHR1 (0.34) | ALDH1A1HPGDTDP1L3MBTL1KDM4E | |
| SCHEMBL16639278 | 0.89 | RXRA (0.31) | ALDH1A1CYP3A4TDP1L3MBTL1KDM4E | |
| SCHEMBL16639279 | 0.89 | RXRA (0.31) | ALDH1A1CYP3A4TDP1L3MBTL1KDM4E | |
| SCHEMBL16639340 | 0.88 | CYP1A2 (0.35) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL16641958 | 0.88 | TNF (0.32) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102290-A1 | DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP | UNIVERSAL DISPLAY CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |