Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15530561 | 0.79 | NAMPT (1.00) | NAMPTALDH1A1 | |
| SCHEMBL15246315 | 0.77 | NAMPT (0.66) | NAMPTTHRBALDH1A1MEN1KMT2A | |
| SCHEMBL16639776 | 0.77 | POLB (0.58) | NAMPTPOLBTHRBALDH1A1MEN1 | |
| SCHEMBL16639790 | 0.74 | ALDH1A1 (0.61) | NAMPTTP53POLBTHRBALDH1A1 | |
| SCHEMBL15246292 | 0.74 | NAMPT (1.00) | NAMPTALDH1A1 | |
| SCHEMBL16639758 | 0.73 | NAMPT (0.98) | NAMPT | |
| SCHEMBL4727111 | 0.73 | ALDH1A1 (0.76) | POLBALDH1A1KMT2A | |
| SCHEMBL16107599 | 0.73 | NAMPT (1.00) | NAMPT | |
| SCHEMBL15246323 | 0.72 | ALDH1A1 (0.60) | NAMPTPOLBALDH1A1 | |
| SCHEMBL23747380 | 0.72 | NAMPT (0.77) | NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | VALO HEALTH, INC. | 2015-04-16 | — | — | US | disclosed |
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | VALO HEALTH, INC. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | STS, SULT1E1, CBS | NAMPT 759/4885TP53 2268/4885POLB 4160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.