Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385884 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 | |
| SCHEMBL27003867 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 | |
| SCHEMBL4251494 | 0.98 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 | |
| SCHEMBL11343298 | 0.95 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 | |
| SCHEMBL28600680 | 0.91 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 | |
| SCHEMBL118235 | 0.91 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 | |
| SCHEMBL28434793 | 0.91 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 | |
| SCHEMBL10621326 | 0.91 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 | |
| SCHEMBL20624816 | 0.91 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 | |
| SCHEMBL4941879 | 0.91 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1EPHX2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150104502-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150104502-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LGALS1, BOLA2; BOLA2B, LGALS2 | ALDH1A1 170/4885MAPK1 2213/4885L3MBTL1 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.