SCHEMBL16640276

SCHEMBL16640276

CC(C)P(c1ccccc1C(c1ccccc1)(c1ccccc1P(C(C)C)C(C)C)c1ccccc1P(C(C)C)C(C)C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
CYP2D6 P10635 2/20 0.32
CYP1A2 P05177 1/20 0.32
APOBEC3A P31941 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
KCNN4 O15554 2/20 0.30
MAPK1 P28482 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP2C19 P33261 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16640281 0.92 CRHBP (0.30) CRHBPCRHR2
SCHEMBL2854576 0.74 SLC6A2 (0.33) ALDH1A1
SCHEMBL4453279 0.73 TAAR1 (0.35) CYP2D6
SCHEMBL30096500 0.73 TAAR1 (0.35) CYP2D6
SCHEMBL28565820 0.66 KCNN4 (0.45) CYP1A2KCNN4MAPK1ALDH1A1CYP2C19
SCHEMBL9632116 0.66 TSHR (0.43) KCNN4MAPK1ALDH1A1
SCHEMBL18280247 0.66 SLC6A2 (0.30)
SCHEMBL16632444 0.66 GABRA1 (0.36) CYP1A2
SCHEMBL18287328 0.66 TAAR1 (0.30)
SCHEMBL7561832 0.66 TSHR (0.43) CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9815694-B2 Catalytic ammonia synthesis by transition metal molecular complexes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2017-11-14 US disclosed
US-20150104371-A1 CATALYTIC AMMONIA SYNTHESIS BY TRANSITION METAL MOLECULAR COMPLEXES CALIFORNIA INSTITUTE OF TECHNOLOGY 2015-04-16 US disclosed