Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.78 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.78 |
| ▸ | MGLL | Q99685 | 7/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15004253 | 0.92 | PTGS2 (0.66) | PTGS1EPHX2PTGS2MGLLALOX5 | |
| SCHEMBL16640306 | 0.90 | PTGS2 (0.65) | PTGS1EPHX2PTGS2MGLLALOX5 | |
| SCHEMBL2917927 | 0.85 | PTGS2 (0.59) | PTGS1EPHX2PTGS2MGLLALOX5 | |
| SCHEMBL16640302 | 0.81 | PTGS2 (0.64) | PTGS1EPHX2PTGS2MGLLALOX5 | |
| SCHEMBL2916474 | 0.76 | KDM4E (0.50) | PTGS1EPHX2PTGS2KMT2AKDM4E | |
| SCHEMBL2921273 | 0.75 | MGLL (0.51) | PTGS1EPHX2PTGS2MGLLMEN1 | |
| SCHEMBL16640308 | 0.74 | KDM1A (0.51) | PTGS1EPHX2PTGS2MGLLMEN1 | |
| SCHEMBL3339277 | 0.74 | TSHR (0.67) | KMT2AKDM4EATMNPC1 | |
| SCHEMBL3144076 | 0.73 | HTR2A (0.67) | PTGS2MGLLMEN1KMT2A | |
| SCHEMBL1514409 | 0.72 | KMT2A (1.00) | MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150105388-A1 | CARBOXAMIDE-SUBSTITUTED HETEROARYL-PYRAZOLES AND THE USE THEREOF | AICURIS GMBH & CO. KG (DE) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105388-A1 | CARBOXAMIDE-SUBSTITUTED HETEROARYL-PYRAZOLES AND THE USE THEREOF | PAICS, AADAC, TPMT | PTGS1 3956/4885EPHX2 2034/4885PTGS2 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.