SCHEMBL16640327

SCHEMBL16640327

CC(C)c1ccc2c3ccccc3n(C(C)C)c2c1C(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPY5R Q15761 6/20 0.36
POLB P06746 3/20 0.36
HTT P42858 1/20 0.36
PRKD3 O94806 1/20 0.36
PRKCG P05129 1/20 0.36
PRKCB P05771 1/20 0.36
PRKCA P17252 1/20 0.36
PRKCH P24723 1/20 0.36
PRKCI P41743 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20053562 0.87 TSHR (0.38) MAPTTSHRMAPK1CASP1CASP7
SCHEMBL23229266 0.85 ALDH1A1 (0.34) MAPTTSHRMAPK1CASP1CASP7
SCHEMBL18610705 0.83 MAPT (0.42) MAPTTSHRMAPK1CASP1CASP7
SCHEMBL16640352 0.81 BCHE (0.43) MAPTTSHRMAPK1CASP1CASP7
SCHEMBL20053525 0.80 TSHR (0.40) MAPTTSHRMAPK1CASP1CASP7
SCHEMBL23046388 0.78 ALDH1A1 (0.44) MAPTTSHRMAPK1CASP1CASP7
SCHEMBL16696126 0.75 TSHR (0.50) MAPTTSHRMAPK1CASP1CASP7
SCHEMBL25702394 0.75 ALKBH5 (0.53) MAPTTSHRMAPK1CASP1CASP7
SCHEMBL29780042 0.74 BCHE (0.59) MAPTTSHRMAPK1CASP1CASP7
SCHEMBL150044 0.74 BCHE (0.59) MAPTTSHRMAPK1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11189808-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-11-30 US disclosed
US-20200373505-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS UNIV ARIZONA STATE (US) 2020-11-26 US disclosed
US-20200152891-A1 PLATINUM COMPLEXES AND DEVICES UNIV ARIZONA STATE (US) 2020-05-14 US disclosed
US-10020455-B2 Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-07-10 US disclosed
US-20180138428-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2018-05-17 US disclosed
US-9947881-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-04-17 US disclosed
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2017-01-12 US disclosed
US-9385329-B2 Platinum complexes and devices Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) 2016-07-05 US disclosed
US-20160043331-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2016-02-11 US disclosed
US-20150194616-A1 Tetradentate Platinum And Palladium Complex Emitters Containing Phenyl-Pyrazole And Its Analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-07-09 US disclosed
US-20150105556-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11189808-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 MAPT 1431/4885TSHR 3038/4885MAPK1 3673/4885
US-20150194616-A1 Tetradentate Platinum And Palladium Complex Emitters Containing Phenyl-Pyrazole And Its Analogues PDCD1, PDCD5, PDCD11 MAPT 717/4885TSHR 1417/4885MAPK1 1277/4885
US-20200152891-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 MAPT 1431/4885TSHR 3038/4885MAPK1 3673/4885
US-20180138428-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS SLC30A6, SLC30A5, BRI3BP MAPT 839/4885TSHR 206/4885MAPK1 4056/4885
US-20160043331-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS SLC30A6, SLC30A5, BRI3BP MAPT 839/4885TSHR 206/4885MAPK1 4056/4885
US-10020455-B2 Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues PDCD1, PDCD11, HPRT1 MAPT 416/4885TSHR 1271/4885MAPK1 1531/4885
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 MAPT 1431/4885TSHR 3038/4885MAPK1 3673/4885
US-20200373505-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS SLC30A6, SLC30A5, BRI3BP MAPT 839/4885TSHR 206/4885MAPK1 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.