SCHEMBL16640692

SCHEMBL16640692

COc1cc(N)ccc1N1CCN(c2ccc(N)cc2CO)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 2/20 0.48
DRD2 P14416 5/20 0.46
DRD4 P21917 4/20 0.46
HRH1 P35367 2/20 0.46
DRD3 P35462 2/20 0.46
MAPT P10636 6/20 0.45
GAA P10253 5/20 0.45
HTT P42858 2/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 3/20 0.43
ALDH1A3 P47895 1/20 0.43
RAD52 P43351 2/20 0.40
GFER P55789 1/20 0.40
KDM4E B2RXH2 3/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HTR2A P28223 1/20 0.40
ADRA1D P25100 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17264118 0.91 NR4A1 (0.43) NR4A1DRD2DRD4HRH1DRD3
SCHEMBL15358685 0.86 NR4A1 (0.61) NR4A1DRD2DRD3MAPTGAA
SCHEMBL189132 0.82 MAPT (0.59) NR4A1MAPTGAAHTTMAPK1
SCHEMBL29507839 0.82 MAPT (0.59) NR4A1MAPTGAAHTTMAPK1
SCHEMBL10036397 0.82 DRD2 (0.49) NR4A1DRD2DRD4DRD3MAPT
SCHEMBL29517510 0.80 MAPT (0.61) NR4A1DRD2DRD4DRD3MAPT
SCHEMBL189143 0.80 MAPT (0.61) NR4A1DRD2DRD4DRD3MAPT
SCHEMBL1930522 0.80 ALDH1A1 (0.59) NR4A1MAPTGAAHTTTSHR
SCHEMBL3175837 0.79 MAPT (0.64) NR4A1DRD2DRD4HRH1DRD3
SCHEMBL1808790 0.79 MAPT (0.64) NR4A1MAPTGAAALDH1A1RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127655-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2018-05-10 US disclosed
US-9909065-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2018-03-06 US disclosed
US-20170327743-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME JNC CORP (JP) 2017-11-16 US disclosed
US-20170327744-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORP (JP) 2017-11-16 US disclosed
US-9796927-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2017-10-24 US disclosed
US-9771519-B2 Liquid crystal display device and method for manufacturing same JNC CORPORATION (JP) 2017-09-26 US disclosed
US-20170227820-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-08-10 US disclosed
US-20170199432-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-07-13 US disclosed
US-20170114277-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-04-27 US disclosed
US-20160369168-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2016-12-22 US disclosed
US-20150329781-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-11-19 US disclosed
US-20150275089-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-10-01 US disclosed
US-20150232665-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF CHI MEI CORPORATION (TW) 2015-08-20 US disclosed
US-20150119522-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2015-04-30 US disclosed
US-20150105503-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-04-16 US disclosed