SCHEMBL16640696

SCHEMBL16640696

COc1cc(N2CCN(c3ccc(N)c(CO)c3)CC2)ccc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.43
ALDH1A1 P00352 5/20 0.41
GAA P10253 2/20 0.41
RAD52 P43351 1/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RECQL P46063 1/20 0.41
PTK2B Q14289 1/20 0.41
SIRT6 Q8N6T7 1/20 0.40
LMNA P02545 1/20 0.39
CCR1 P32246 2/20 0.39
SUV39H2 Q9H5I1 3/20 0.39
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17264114 0.91 LGMN (0.40) HTR7ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL15358736 0.86 ALDH1A1 (0.53) HTR7ALDH1A1GAARAD52CYP3A4
SCHEMBL10061499 0.82 KDM4E (0.61) ALDH1A1GAARAD52KDM4EMAPT
SCHEMBL2234370 0.82 GAA (0.47) HTR7GAARAD52HSD17B10SUV39H2
SCHEMBL3309196 0.81 GAA (0.40) HTR7ALDH1A1GAARAD52CYP3A4
SCHEMBL13362045 0.81 MAPT (0.41) HTR7ALDH1A1GAARAD52CYP3A4
SCHEMBL29446146 0.80 MAPT (0.63) ALDH1A1GAACYP3A4TSHRHSD17B10
SCHEMBL438444 0.80 MAPT (0.63) ALDH1A1GAACYP3A4TSHRHSD17B10
SCHEMBL2974453 0.80 ALDH1A1 (0.59) ALDH1A1GAACYP3A4TSHRHSD17B10
SCHEMBL3315822 0.80 TMEM97 (0.39) HTR7ALDH1A1GAARAD52CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9909065-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2018-03-06 US disclosed
US-20170327744-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORP (JP) 2017-11-16 US disclosed
US-20170327743-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME JNC CORP (JP) 2017-11-16 US disclosed
US-9796927-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2017-10-24 US disclosed
US-9771519-B2 Liquid crystal display device and method for manufacturing same JNC CORPORATION (JP) 2017-09-26 US disclosed
US-20170227820-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-08-10 US disclosed
US-20170199432-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-07-13 US disclosed
US-20170114277-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-04-27 US disclosed
US-20160369168-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2016-12-22 US disclosed
US-20150329781-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-11-19 US disclosed
US-20150275089-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-10-01 US disclosed
US-20150232665-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF CHI MEI CORPORATION (TW) 2015-08-20 US disclosed
US-20150119522-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2015-04-30 US disclosed
US-20150105503-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-04-16 US disclosed