SCHEMBL16640697

SCHEMBL16640697

CCOc1cc(N2CCN(c3ccc(N)c(C)c3)CC2)ccc1N

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.64
RAD52 P43351 2/20 0.64
MAPT P10636 9/20 0.50
KDM4E B2RXH2 4/20 0.50
MAPK1 P28482 4/20 0.50
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 3/20 0.50
HSD17B10 Q99714 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
POLB P06746 1/20 0.50
HPGD P15428 1/20 0.50
LMNA P02545 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
LGMN Q99538 2/20 0.42
HTT P42858 4/20 0.42
RECQL P46063 1/20 0.42
PTK2B Q14289 1/20 0.42
S1PR1 P21453 1/20 0.42
RAB9A P51151 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15358735 0.92 MAPT (0.58) GAARAD52MAPTKDM4EMAPK1
SCHEMBL29508973 0.87 MAPT (0.58) GAARAD52MAPTKDM4EMAPK1
SCHEMBL1912036 0.87 MAPT (0.58) GAARAD52MAPTKDM4EMAPK1
SCHEMBL1911970 0.86 MAPT (0.59) GAARAD52MAPTKDM4EMAPK1
SCHEMBL16640693 0.86 GAA (0.58) GAARAD52MAPTKDM4EMAPK1
SCHEMBL18784998 0.84 MAPT (0.49) GAARAD52MAPTKDM4EMAPK1
SCHEMBL310612 0.83 DRD2 (0.51) GAARAD52MAPTKDM4EMAPK1
SCHEMBL309692 0.83 MAPT (0.47) GAARAD52MAPTKDM4EMAPK1
SCHEMBL17264109 0.82 MAPT (0.50) GAARAD52MAPTKDM4EMAPK1
SCHEMBL1912077 0.82 LGMN (0.56) GAARAD52MAPTKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127655-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2018-05-10 US disclosed
US-9909065-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2018-03-06 US disclosed
US-20170327743-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME JNC CORP (JP) 2017-11-16 US disclosed
US-20170327744-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORP (JP) 2017-11-16 US disclosed
US-9796927-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2017-10-24 US disclosed
US-9771519-B2 Liquid crystal display device and method for manufacturing same JNC CORPORATION (JP) 2017-09-26 US disclosed
US-20170227820-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-08-10 US disclosed
US-20170199432-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-07-13 US disclosed
US-20170114277-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-04-27 US disclosed
US-20160369168-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2016-12-22 US disclosed
US-20150275089-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-10-01 US disclosed
US-20150119522-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2015-04-30 US disclosed
US-20150105503-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-04-16 US disclosed