SCHEMBL16640955

SCHEMBL16640955

CCCCNC(=O)N(C(=O)NCCC[Si](OCC)(OCC)OCC)c1ccc(Cc2ccc(N(CC3CO3)CC3CO3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.32
BCHE P06276 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CNR2 P34972 1/20 0.31
LTB4R2 Q9NPC1 1/20 0.31
ALDH1A1 P00352 1/20 0.30
PKM P14618 1/20 0.30
ESRRG P62508 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19901213 0.97 ALOX5 (0.35) ALOX5
SCHEMBL16641015 0.91 ALOX5 (0.45) ALOX5HPGDKDM4EBCHEMEN1
SCHEMBL16640973 0.89 ALOX5 (0.38) ALOX5HPGDBCHEMEN1KMT2A
SCHEMBL20226256 0.87 HPGD (0.38) ALOX5HPGDLTB4R2ALDH1A1
SCHEMBL19901220 0.86 ALOX5 (0.34) ALOX5HPGDMEN1KMT2AALDH1A1
SCHEMBL16640937 0.83 HTT (0.32)
SCHEMBL16640966 0.82 ALOX5 (0.44) ALOX5HPGDKDM4EBCHEMEN1
SCHEMBL19901210 0.81
SCHEMBL16640957 0.81 ALOX5 (0.38) ALOX5HPGDBCHEMEN1KMT2A
SCHEMBL16640965 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9902803-B2 Epoxy compound having alkoxy silyl group, composition comprising same, cured product, use thereof and method for preparing epoxy compound having alkoxy silyl group KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-27 US disclosed
US-20150105493-A1 EPOXY COMPOUND HAVING ALKOXY SILYL GROUP, COMPOSITION COMPRISING SAME, CURED PRODUCT, USE THEREOF AND METHOD FOR PREPARING EPOXY COMPOUND HAVING ALKOXY SILYL GROUP KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2015-04-16 US disclosed