SCHEMBL19901220

SCHEMBL19901220

CCO[Si](CCCNC(=O)N(C(=O)NCCC[Si](OCC)(OCC)OCC)c1ccc(C(C)(C)c2ccc(C(C)(C)c3ccc(N(CC4CO4)CC4CO4)cc3)cc2)cc1)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33
CYP1A2 P05177 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PPARG P37231 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16640973 0.97 ALOX5 (0.38) ALOX5MEN1KMT2ATP53MAPT
SCHEMBL16641033 0.94 ALOX5 (0.32) ALOX5MEN1KMT2ATP53MAPT
SCHEMBL16640944 0.93 TP53 (0.32) ALOX5MEN1KMT2ATP53MAPT
SCHEMBL19901221 0.91 ALOX5 (0.33) ALOX5MEN1KMT2ATP53MAPT
SCHEMBL16640957 0.89 ALOX5 (0.38) ALOX5MEN1KMT2ATP53MAPT
SCHEMBL19901213 0.88 ALOX5 (0.35) ALOX5
SCHEMBL19901222 0.88 TP53 (0.34) ALOX5MEN1KMT2ATP53MAPT
SCHEMBL16640955 0.86 ALOX5 (0.39) ALOX5MEN1KMT2AHPGDALDH1A1
SCHEMBL16641023 0.85 TP53 (0.39) MEN1KMT2ATP53MAPTHPGD
SCHEMBL19901217 0.84 TP53 (0.39) MEN1KMT2ATP53MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9902803-B2 Epoxy compound having alkoxy silyl group, composition comprising same, cured product, use thereof and method for preparing epoxy compound having alkoxy silyl group KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-27 US disclosed