SCHEMBL1664153

SCHEMBL1664153

CC(C)CNc1c[c]cc(NCC(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.41
AR P10275 2/20 0.33
ESR2 Q92731 1/20 0.33
TRPA1 O75762 1/20 0.32
PSEN1 P49768 1/20 0.32
PSEN2 P49810 1/20 0.32
APH1B Q8WW43 1/20 0.32
NCSTN Q92542 1/20 0.32
APH1A Q96BI3 1/20 0.32
PSENEN Q9NZ42 1/20 0.32
HRH4 Q9H3N8 3/20 0.32
IDO1 P14902 1/20 0.32
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5121927 0.82 TRPA1 (0.42) ESR1ARTRPA1MAPT
SCHEMBL1664892 0.75 IDO1 (0.35) ESR1ARIDO1MAPTMAPK1
SCHEMBL8086220 0.73 MAPT (0.34) MAPT
SCHEMBL1664353 0.73 ESR1 (0.36) ESR1ARPSEN1PSEN2APH1B
SCHEMBL146034 0.72 IDO1 (0.45) ESR1ARPSEN1PSEN2APH1B
SCHEMBL1666778 0.71 IDO1 (0.38) ESR1IDO1MAPTMAPK1TDP1
SCHEMBL1664974 0.71 ESR1 (0.39) ESR1ARESR2TRPA1PSEN1
SCHEMBL17852352 0.70 THRB (0.45) ESR1MAPTMAPK1TDP1L3MBTL1
SCHEMBL30288276 0.68 ESR1 (0.48) ESR1PSEN1PSEN2APH1BNCSTN
SCHEMBL16486695 0.67 SCN1A (0.37) ESR1ARTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 US disclosed
US-7922947-B2 Method of producing dispersion FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
US-7166339-B1 Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound FUJIFILM CORPORATION (JP) 2007-01-23 US disclosed
US-20060216437-A1 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2006-09-28 US disclosed
US-20050062193-A1 Method of producing dispersion FUJIFILM CORPORATION (JP) 2005-03-24 US disclosed
CN-1173198-C Phase retardation plate comprising cellulose ester film, circularly polarizing plate and liquid crystal display device 富士胶片株式会社 2004-10-27 CN disclosed
US-6630973-B1 Compensatory sheet, ellipsoidal polarizing plate and liquid crystal display. FUJI PHOTO FILM CO., LTD. (JP) 2003-10-07 US disclosed
CN-1348547-A Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound FUJI PHOTO FILM CO LTD (JP) 2002-05-08 CN disclosed
EP-1182470-A1 PHASE CONTRAST PLATE COMPRISING ONE SHEET OF CELLULOSE ESTER FILM CONTAINING AROMATIC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2002-02-27 EP disclosed