Sugi Predict

Sugi Predict / Compounds / Methacrylic Acid

Methacrylic Acid

Methacrylic Acid

SCHEMBL1664193

C=C(C)C(=O)O.C=CC(=O)OCCOC(=O)C=C

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 10/20 0.61
▸ ALDH1A1 P00352 5/20 0.61
▸ TP53 P04637 3/20 0.61
▸ HIF1A Q16665 3/20 0.61
▸ HSD17B10 Q99714 2/20 0.61
▸ CYP3A4 P08684 2/20 0.56
▸ HPGD P15428 1/20 0.55
▸ THRB P10828 4/20 0.50
▸ MAPK1 P28482 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ HCAR2 Q8TDS4 2/20 0.36
▸ ALOX15 P16050 1/20 0.34
▸ ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL16197602 0.94 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL16114495 0.92 TSHR (0.53) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL5028039 0.90 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL1085237 0.90 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL10949902 0.90 TSHR (0.60) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL14060439 0.89 HCAR2 (0.55) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL6060812 0.89 TSHR (0.60) TSHRALDH1A1TP53HIF1AHSD17B10
Acetic Acid SCHEMBL3361156 0.89 TSHR (0.70) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL28330760 0.88 TSHR (0.48) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL28812158 0.88 TSHR (0.70) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6458726-B1 BLEND WITH BOND CURVE ENHANCING AGENT ETHYLENE-VINYL ACETATE COPOLYMER; HIGH CROSS-DIRECTIONAL STRENGTH; DIAPERS FIBERCO, INC. 2002-10-01 — — US claimed
US-5985193-A EXTRUDING A POLYMER BLEND COMPRISING POLYPROPYLENE AND ETHYLENE VINYL ACETATE POLYMER FIBERCO., INC. (US) 1999-11-16 — — US claimed
EP-0891433-A1 POLYPROPYLENE FIBERS AND ITEMS MADE THEREFROM HERCULES INCORPORATED (US) 1999-01-20 — — EP claimed
WO-1997037065-A1 POLYPROPYLENE FIBERS AND ITEMS MADE THEREFROM HERCULES INCORPORATED (US) 1997-10-09 — — WO claimed
WO-2024106520-A1 NON-STICKY STABLE COMPOSITION WITH TEXTURE TRANSFORMATION PROPERTY L'OREAL (FR) 2024-05-23 — — WO disclosed
US-11884804-B2 Foam body, polyolefin-based foam sheet, and complex MITSUI CHEMICALS, INC. (JP) 2024-01-30 — — US disclosed
WO-2022124385-A1 OIL-IN-WATER EMULSION COMPOSITION L'OREAL (FR) 2022-06-16 — — WO disclosed
US-11090252-B2 Process for straightening keratin fibres with a composition comprising a urea and/or a urea derivative and a polymeric thickener L'OREAL (FR) 2021-08-17 — — US disclosed
EP-2988830-B1 COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF OREAL (FR) 2021-03-17 — — EP disclosed
EP-3578596-A1 FOAM BODY, POLYOLEFIN-BASED FOAM SHEET AND COMPLEX Mitsui Chemicals, Inc. (JP) 2019-12-11 — — EP disclosed
US-20190117551-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER L'OREAL (FR) 2019-04-25 — — US disclosed
WO-2019008937-A1 FOAMING CLEANSER L'OREAL (FR) 2019-01-10 — — WO disclosed
EP-0891433-B1 POLYPROPYLENE FIBERS AND ITEMS MADE THEREFROM FIBERVISIONS L P (US) 2003-05-07 — — EP disclosed
US-6458726-B1 BLEND WITH BOND CURVE ENHANCING AGENT ETHYLENE-VINYL ACETATE COPOLYMER; HIGH CROSS-DIRECTIONAL STRENGTH; DIAPERS FIBERCO, INC. 2002-10-01 — — US disclosed
US-5985193-A EXTRUDING A POLYMER BLEND COMPRISING POLYPROPYLENE AND ETHYLENE VINYL ACETATE POLYMER FIBERCO., INC. (US) 1999-11-16 — — US disclosed
EP-0891433-A1 POLYPROPYLENE FIBERS AND ITEMS MADE THEREFROM HERCULES INCORPORATED (US) 1999-01-20 — — EP disclosed
WO-1997037065-A1 POLYPROPYLENE FIBERS AND ITEMS MADE THEREFROM HERCULES INCORPORATED (US) 1997-10-09 — — WO disclosed
US-4987199-A Low deformation during vulcanization, high dimensional accuracy SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-22 — — US disclosed
EP-0341268-A4 FLEXIBLE THERMOPLASTIC COMPOSITION — 1991-01-16 — — EP disclosed
WO-1989004346-A1 FLEXIBLE THERMOPLASTIC COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11090252-B2 Process for straightening keratin fibres with a composition comprising a urea and/or a urea derivative and a polymeric thickener KRT18, CUTA, MARK1 TSHR 4385/4885ALDH1A1 2616/4885TP53 1696/4885
US-20190117551-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER KRT18, CUTA, MARK1 TSHR 4385/4885ALDH1A1 2616/4885TP53 1696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.