SCHEMBL16641978

SCHEMBL16641978

CCSC1CC(=O)N(CCCC(=O)NCCO[C@@H]2OC(OC=O)[C@@H](O[C@H]3OC(CO)[C@@H](O[C@@H]4OC(OC=O)[C@@H](OC)[C@H](O)C4O)[C@H](O)C3NC(C)=O)[C@H](O)C2O)C1=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MDK P21741 4/20 0.43
LGALS3 P17931 8/20 0.40
LGALS8 O00214 1/20 0.40
LGALS4 P56470 1/20 0.40
MMP13 P45452 1/20 0.35
LGALS9 O00182 2/20 0.33
CHIA Q9BZP6 1/20 0.33
MAPK1 P28482 1/20 0.33
LGALS7; LGALS7B P47929 2/20 0.33
LGALS1 P09382 1/20 0.33
OGA O60502 1/20 0.32
HPSE Q9Y251 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16645717 0.91 MDK (0.50) MDKLGALS3LGALS8LGALS4MMP13
SCHEMBL18473097 0.88 MDK (0.41) MDKLGALS3LGALS8LGALS4MMP13
SCHEMBL18494424 0.80 MDK (0.47) MDKLGALS3LGALS8LGALS4MMP13
SCHEMBL18494423 0.80 MDK (0.47) MDKLGALS3LGALS8LGALS4MMP13
SCHEMBL17849186 0.74 LGALS3 (0.54) LGALS3LGALS8LGALS4LGALS9CHIA
SCHEMBL17849185 0.73 LGALS3 (0.54) LGALS3LGALS8LGALS4LGALS9CHIA
SCHEMBL16641974 0.73 LGALS3 (0.54) LGALS3LGALS8LGALS4LGALS9CHIA
SCHEMBL17849184 0.73 LGALS3 (0.46) MDKLGALS3LGALS8LGALS4LGALS9
SCHEMBL16641976 0.73 LGALS3 (0.46) MDKLGALS3LGALS8LGALS4LGALS9
SCHEMBL20175842 0.72 LGALS3 (0.52) LGALS3LGALS8LGALS4LGALS9CHIA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9370583-B2 Coagulation factor VII polypeptides NOVO NORDISK HEALTHCARE AG (CH) 2016-06-21 US disclosed
US-9371370-B2 Coagulation factor VII polypeptides NOVO NORDISK HEALTHCARE AG (CH) 2016-06-21 US disclosed
US-20150105321-A1 COAGULATION FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTHCARE AG (CH) 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150105321-A1 COAGULATION FACTOR VII POLYPEPTIDES F7, F13B, HABP2 MDK 2724/4885LGALS3 2458/4885LGALS8 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.