Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16641990 | 0.90 | MAPT (0.57) | KMT2AMEN1HPGDLMNAPOLB | |
| SCHEMBL16645384 | 0.84 | CA1 (0.52) | KMT2AMEN1HPGDLMNAPOLB | |
| SCHEMBL12767425 | 0.82 | MAPT (0.51) | KMT2AMEN1LMNAMAPTGAA | |
| SCHEMBL16641986 | 0.82 | CA1 (0.64) | KMT2AMEN1HPGDLMNAPOLB | |
| SCHEMBL16641992 | 0.79 | KMT2A (0.58) | KMT2AMEN1HPGDLMNAPOLB | |
| SCHEMBL12204318 | 0.79 | KMT2A (0.51) | KMT2AMEN1HPGDLMNAPOLB | |
| SCHEMBL16645385 | 0.77 | MEN1 (0.61) | KMT2AMEN1HPGDLMNAPOLB | |
| SCHEMBL11046759 | 0.76 | HDAC1 (0.47) | KMT2AMEN1LMNAMAPTGAA | |
| SCHEMBL16641989 | 0.73 | ACLY (0.52) | KMT2AMEN1HPGDLMNAPOLB | |
| SCHEMBL16641984 | 0.73 | ALB (0.61) | KMT2AMEN1HPGDLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150105324-A1 | COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105324-A1 | COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES | GRIN2A, GRIN1, GRIN2C | KMT2A 1058/4885MEN1 4328/4885HPGD 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.