Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.45 |
| ▸ | NPC1 | O15118 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12790164 | 0.93 | MAOB (0.45) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL13974462 | 0.82 | MAOB (0.49) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL1663552 | 0.80 | MEN1 (0.47) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL1664078 | 0.80 | MAPT (0.49) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL27918331 | 0.79 | MAOB (0.47) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL1664696 | 0.79 | MCHR1 (0.52) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL18745969 | 0.79 | MAOB (0.46) | MAPTMAOBMAPK10MAPK8 | |
| SCHEMBL1666277 | 0.78 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL6125796 | 0.78 | MAPT (0.50) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL1666916 | 0.78 | MAPT (0.52) | RAB9ANPC1SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |