SCHEMBL1664309

SCHEMBL1664309

CCCCCCCCCCCCOc1c[c]ccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.51
TSHR P16473 2/20 0.51
NR5A1 Q13285 1/20 0.49
MLNR O43193 1/20 0.45
NR1I2 O75469 1/20 0.45
ESR1 P03372 1/20 0.45
NR3C1 P04150 1/20 0.45
PGR P06401 1/20 0.45
ADRB2 P07550 1/20 0.45
CHRM2 P08172 1/20 0.45
ADRB1 P08588 1/20 0.45
HTR1A P08908 1/20 0.45
ADRA2A P08913 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
CHRM1 P11229 1/20 0.45
DRD2 P14416 1/20 0.45
ADRA2B P18089 1/20 0.45
ADRA2C P18825 1/20 0.45
CHRM3 P20309 1/20 0.45
MAOA P21397 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920303 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2
SCHEMBL1664741 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2
SCHEMBL6536652 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2
SCHEMBL6050554 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2
SCHEMBL677306 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2
SCHEMBL8420511 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2
SCHEMBL5014110 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2
SCHEMBL533346 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2
SCHEMBL9796880 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2
SCHEMBL6682729 1.00 LTA4H (0.51) LTA4HTSHRNR5A1MLNRNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312337-B2 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY (US) 2007-12-25 US claimed
US-7268235-B2 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY (US) 2007-09-11 US claimed
US-20060074245-A1 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY 2006-04-06 US claimed
US-20060069262-A1 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY 2006-03-30 US claimed
US-7922947-B2 Method of producing dispersion FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
CN-100454053-C Method for producing optical compensation film, optical compensation film, polarizing plate, displaying apparatus KONICA MINOLTA OPTO INC (JP) 2009-01-21 CN disclosed
US-7359017-B2 Optical compensation film, polarizing plate, displaying apparatus, method for producing optical compensation film and method for producing polarizing plate KONICA MINOLTA OPTO, INC. (JP) 2008-04-15 US disclosed
US-7312337-B2 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY (US) 2007-12-25 US disclosed
US-7268235-B2 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY (US) 2007-09-11 US disclosed
CN-1975473-A Optical compensation film, viewing angle compensation integral type polarizing plate and liquid crystal display apparatus KONICA MINOLTA HOLDINGS INC (JP) 2007-06-06 CN disclosed
CN-1312491-C Optical compensation film, viewing angle compensation integral type polarizing plate and liquid crystal display device KONICA MINOLTA HOLDINGS INC (JP) 2007-04-25 CN disclosed
US-7205083-B2 Recording material FUJIFILM CORPORATION (JP) 2007-04-17 US disclosed
US-4069227-A POLYMERS EASTMAN KODAK COMPANY (US) 1978-01-17 US disclosed
US-4052214-A COLOR DIFFUSION TRANSFER PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FOR FORMING BOTH POSITIVE TRANSFER DYE IMAGES AND NEGATIVE DYE IMAGES FUJI PHOTO FILM CO., LTD. (JA) 1977-10-04 US disclosed
US-4020041-A Polymers stabilized with bis-heterocyclic benzoates EASTMAN KODAK COMPANY (US) 1977-04-26 US disclosed
US-4020080-A Oxadiazolylphenyl aromatic ester compounds and their use as ultraviolet stabilizer in organic compositions EASTMAN KODAK COMPANY (US) 1977-04-26 US disclosed
US-4015989-A Color light-sensitive material with spontaneously developable silver halide emulsion containing desensitizing dye FUJI PHOTO FILM CO., LTD. (JA) 1977-04-05 US disclosed
US-3963738-A Bis-oxadiazolyl phenyl aromatic diester compounds and their use as ultraviolet stabilizers in organic compositions EASTMAN KODAK COMPANY (US) 1976-06-15 US disclosed
US-3960569-A Diffusion transfer color film unit with hydroxy substituted alkylene amino development accelerators FUJI PHOTO FILM CO., LTD. (JA) 1976-06-01 US disclosed
US-3957813-A BENZOXAZOLYL PHENYL AROMATIC ESTER COMPOUNDS AND THEIR USE AS ULTRAVIOLET STABILIZERS IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060069262-A1 Oxadiazoles and their manufacture OXA1L, CYP1B1, OXER1 LTA4H 2670/4885TSHR 1486/4885NR5A1 1283/4885
US-20060074245-A1 Method for preparation of N-pyrazolylamidoximes KCNH1, KCNJ2, KCNH2 LTA4H 2138/4885TSHR 1694/4885NR5A1 1937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.