Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16482164 | 0.61 | IL2 (0.54) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL16225675 | 0.60 | DAO (0.41) | GAAPKMALOX15HSD17B10KDM4E | |
| SCHEMBL147222 | 0.60 | — | — | |
| SCHEMBL29241940 | 0.60 | CES2 (0.37) | GAAKDM4EALDH1A1NPSR1CES2 | |
| SCHEMBL1680441 | 0.60 | TNFRSF1A (0.38) | GAALMNAKDM4EPOLBALDH1A1 | |
| SCHEMBL28770002 | 0.60 | — | — | |
| Trifluoroacetic Acid SCHEMBL4634305 | 0.59 | DAO (0.40) | GAAPKMALOX15HSD17B10LMNA | |
| SCHEMBL12113186 | 0.58 | MAPT (0.61) | GAAHSD17B10LMNAKDM4EPOLB | |
| SCHEMBL12440049 | 0.58 | MAPT (0.61) | GAAHSD17B10LMNAKDM4EPOLB | |
| SCHEMBL9253909 | 0.58 | MAPT (0.61) | GAAHSD17B10LMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054283-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2015-04-16 | — | — | WO | disclosed |