Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664393 | 0.84 | ALDH1A1 (0.35) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR | |
| SCHEMBL1664991 | 0.76 | TSHR (0.39) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR | |
| SCHEMBL1664274 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR | |
| SCHEMBL1664673 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR | |
| SCHEMBL1665018 | 0.72 | TSHR (0.39) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR | |
| SCHEMBL1664415 | 0.69 | ALDH1A1 (0.37) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR | |
| SCHEMBL27655556 | 0.68 | AKT1 (0.45) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR | |
| SCHEMBL16344589 | 0.68 | CETP (0.50) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR | |
| SCHEMBL1665063 | 0.67 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR | |
| SCHEMBL28300763 | 0.67 | ALDH1A1 (0.41) | ALDH1A1MAPK1L3MBTL1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071674-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-06-16 | — | — | WO | disclosed |
| EP-2307476-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20100113664-A1 | Asymmetric Cyclic Diester Compounds | FERRO CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2009152068-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |
| US-20090312470-A1 | Asymmetric Cyclic Diester Compounds | FERRO CORPORATION (US) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312470-A1 | Asymmetric Cyclic Diester Compounds | DDT, PCNA, AADAC | ALDH1A1 585/4885MAPK1 4135/4885L3MBTL1 4045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.