Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16344589 | 0.82 | CETP (0.50) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL1664848 | 0.81 | KMT2A (0.46) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL16347174 | 0.79 | CETP (0.50) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL16344798 | 0.78 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL16345450 | 0.78 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL16345546 | 0.78 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL472086 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPK1TDP1L3MBTL1DDB1 | |
| SCHEMBL22441539 | 0.75 | CPB2 (0.34) | CETPMEN1KMT2A | |
| SCHEMBL11368685 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPK1TDP1L3MBTL1DDB1 | |
| SCHEMBL28300763 | 0.73 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071674-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-06-16 | — | — | WO | disclosed |
| EP-2307476-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20100113664-A1 | Asymmetric Cyclic Diester Compounds | FERRO CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2009152068-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |