SCHEMBL16644751

SCHEMBL16644751

CCOc1cc(N)ccc1N1CCN(c2ccc(N)cc2OCC)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.53
GAA P10253 5/20 0.53
KDM4E B2RXH2 4/20 0.53
RAD52 P43351 3/20 0.50
GFER P55789 2/20 0.50
ALDH1A1 P00352 7/20 0.48
HSD17B10 Q99714 1/20 0.48
DRD2 P14416 2/20 0.47
DRD4 P21917 2/20 0.47
DRD3 P35462 2/20 0.47
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
BRAF P15056 1/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
THRB P10828 1/20 0.45
NR4A1 P22736 1/20 0.45
PTK2B Q14289 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18537687 0.94 MAPT (0.53) MAPTGAAKDM4ERAD52GFER
SCHEMBL25565665 0.94 MAPT (0.56) MAPTGAAKDM4ERAD52GFER
SCHEMBL16640694 0.92 MAPT (0.62) MAPTGAAKDM4ERAD52GFER
SCHEMBL15652180 0.92 GAA (0.62) MAPTGAAKDM4ERAD52GFER
SCHEMBL30309526 0.92 GAA (0.62) MAPTGAAKDM4ERAD52GFER
SCHEMBL13419661 0.92 ALDH1A1 (0.54) MAPTGAAKDM4ERAD52GFER
SCHEMBL18444866 0.91 MAPT (0.45) MAPTGAAKDM4ERAD52GFER
SCHEMBL13723923 0.91 SMN1; SMN2 (0.58) MAPTGAAKDM4EALDH1A1HSD17B10
SCHEMBL13724223 0.85 MAPT (0.43) MAPTGAAKDM4ERAD52GFER
SCHEMBL24904153 0.85 BRAF (0.42) MAPTGAAKDM4ERAD52GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10435627-B2 Liquid crystal display device JNC CORPORATION (JP) 2019-10-08 US disclosed
US-10175538-B2 Liquid crystal display device JNC CORPORATION (JP) 2019-01-08 US disclosed
US-9909065-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2018-03-06 US disclosed
US-20170327743-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME JNC CORP (JP) 2017-11-16 US disclosed
US-20170327744-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORP (JP) 2017-11-16 US disclosed
US-9796927-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2017-10-24 US disclosed
US-9771519-B2 Liquid crystal display device and method for manufacturing same JNC CORPORATION (JP) 2017-09-26 US disclosed
US-20170227820-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-08-10 US disclosed
US-20170199432-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-07-13 US disclosed
US-20170114277-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-04-27 US disclosed
US-20160369168-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2016-12-22 US disclosed
US-20150275089-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-10-01 US disclosed
US-20150119522-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2015-04-30 US disclosed
US-20150105503-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-04-16 US disclosed