Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | RAD52 | P43351 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16644751 | 0.94 | MAPT (0.53) | MAPTKDM4ERAD52ALDH1A1L3MBTL1 | |
| SCHEMBL30879147 | 0.88 | MAPT (0.54) | MAPTKDM4ERAD52ALDH1A1L3MBTL1 | |
| SCHEMBL18537687 | 0.88 | MAPT (0.53) | MAPTKDM4ERAD52ALDH1A1L3MBTL1 | |
| SCHEMBL6972479 | 0.88 | MAPT (0.53) | MAPTKDM4ERAD52ALDH1A1L3MBTL1 | |
| SCHEMBL10127415 | 0.87 | FGFR3 (0.50) | MAPTKDM4ERAD52ALDH1A1PTK2B | |
| SCHEMBL30309526 | 0.87 | GAA (0.62) | MAPTKDM4ERAD52ALDH1A1GAA | |
| SCHEMBL15652180 | 0.87 | GAA (0.62) | MAPTKDM4ERAD52ALDH1A1GAA | |
| SCHEMBL16640694 | 0.87 | MAPT (0.62) | MAPTKDM4ERAD52ALDH1A1GAA | |
| SCHEMBL13419661 | 0.86 | ALDH1A1 (0.54) | MAPTKDM4ERAD52ALDH1A1L3MBTL1 | |
| SCHEMBL23567036 | 0.85 | MAPT (0.54) | MAPTKDM4ERAD52ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094310-A1 | PYRAZOLOTRIAZINE DERIVATIVES USEFUL AS CDK9 INHIBITORS | ORIGENIS GMBH (DE) | 2023-06-01 | — | — | WO | disclosed |