Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21849119 | 1.00 | LTA4H (0.47) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL21208111 | 1.00 | LTA4H (0.47) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL21208104 | 0.97 | ANPEP (0.48) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL19155027 | 0.91 | LTA4H (0.48) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL25100491 | 0.90 | LTA4H (0.46) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL16791610 | 0.89 | ANPEP (0.48) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL22299573 | 0.88 | HSD17B10 (0.44) | LTA4H | |
| SCHEMBL17469339 | 0.88 | LTA4H (0.48) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL20833532 | 0.88 | ANPEP (0.50) | LTA4HSPHK1SPHK2ANPEP | |
| SCHEMBL25100584 | 0.87 | SIRT2 (0.43) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054659-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. (US) | 2015-04-16 | — | — | WO | disclosed |