Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25148090 | 0.91 | HSD17B10 (0.44) | HSD17B10NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21205411 | 0.89 | HSD17B10 (0.43) | HSD17B10NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21849119 | 0.88 | LTA4H (0.47) | LTA4H | |
| SCHEMBL21208111 | 0.88 | LTA4H (0.47) | LTA4H | |
| SCHEMBL16645072 | 0.88 | LTA4H (0.47) | LTA4H | |
| SCHEMBL19443237 | 0.87 | SIRT2 (0.43) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL25100584 | 0.87 | SIRT2 (0.43) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL21208104 | 0.85 | ANPEP (0.48) | LTA4HSIRT2SIRT1SIRT3 | |
| SCHEMBL18099876 | 0.84 | HSD17B10 (0.49) | HSD17B10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL17086814 | 0.84 | SIRT2 (0.44) | HTTSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156513-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | 同宜医药（苏州）有限公司 | 2020-08-06 | — | — | WO | disclosed |