Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 10/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16645117 | 1.00 | REN (0.40) | RENACEACE2PTPN1TSHR | |
| SCHEMBL16645063 | 0.93 | REN (0.41) | RENACEACE2PTPN1TSHR | |
| SCHEMBL16645035 | 0.92 | REN (0.42) | RENACEACE2TSHRATM | |
| SCHEMBL17381551 | 0.91 | REN (0.41) | RENACEACE2PTPN1ATM | |
| SCHEMBL26536406 | 0.90 | REN (0.40) | RENACEACE2PTPN1TSHR | |
| SCHEMBL16645137 | 0.90 | REN (0.41) | RENACEACE2PTPN1TSHR | |
| SCHEMBL23029760 | 0.88 | ATM (0.46) | RENACEACE2ATML3MBTL1 | |
| SCHEMBL17346544 | 0.88 | ACE (0.45) | ACEACE2ATML3MBTL1 | |
| SCHEMBL16645069 | 0.87 | REN (0.40) | RENACEACE2PTPN1TSHR | |
| SCHEMBL22810884 | 0.86 | ACE (0.41) | ACEACE2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054669-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | ASANA BIOSCIENCES, LLC (US) | 2015-04-16 | — | — | WO | disclosed |