Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 1/20 | 0.75 |
| ▸ | RPA1 | P27694 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | XDH | P47989 | 8/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984638 | 0.89 | ADH5 (0.95) | ADH5RPA1ATMXDHTP53 | |
| SCHEMBL12818241 | 0.80 | GP6 (0.65) | ADH5RPA1ATMXDHTP53 | |
| SCHEMBL467316 | 0.78 | ATM (1.00) | ADH5RPA1ATMXDHTP53 | |
| SCHEMBL1777649 | 0.78 | ADH5 (0.75) | ADH5RPA1ATMXDHTP53 | |
| SCHEMBL14347139 | 0.78 | ADH5 (0.75) | ADH5RPA1ATMXDHTP53 | |
| SCHEMBL2667739 | 0.78 | ADH5 (0.75) | ADH5RPA1ATMXDHTP53 | |
| SCHEMBL17208852 | 0.78 | ADH5 (0.75) | ADH5RPA1ATMXDHTP53 | |
| SCHEMBL1248039 | 0.78 | ADH5 (0.75) | ADH5RPA1ATMXDHTP53 | |
| SCHEMBL8295416 | 0.78 | RPA1 (1.00) | ADH5RPA1ATMXDHTP53 | |
| SCHEMBL2645809 | 0.78 | ADH5 (0.75) | ADH5RPA1ATMXDHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020145250-A1 | 15-PGDH INHIBITOR | 杏林製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |