SCHEMBL166454

SCHEMBL166454

CCC(=O)C(C)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9315437 1.00
Benzene SCHEMBL11242418 0.95 FFAR3 (0.38)
SCHEMBL31174525 0.88 ALDH1A1 (0.37)
SCHEMBL2546877 0.84 ALDH1A1 (0.41)
Toluene SCHEMBL6905809 0.81 TSHR (0.42)
SCHEMBL10412722 0.81 ACE2 (0.47)
SCHEMBL16612661 0.79 TDP1 (0.41)
Methylmalonic Acid SCHEMBL995094 0.79 FFAR3 (0.62)
SCHEMBL28279631 0.79 TDP1 (0.37)
SCHEMBL93138 0.78 HDAC1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238230-A1 METHODS OF MODULATION OF BRANCHED CHAIN ACIDS AND USES THEREOF BAYLOR COLLEGE OF MEDICINE 2024-07-18 US claimed
US-20230383319-A1 ITERATIVE PLATFORM FOR THE SYNTHESIS OF ALPHA FUNCTIONALIZED PRODUCTS Gonzalez, Ramon (US) 2023-11-30 US claimed
US-11786494-B2 Methods of modulation of branched chain acids and uses thereof BAYLOR COLLEGE OF MEDICINE (US) 2023-10-17 US claimed
CN-116854578-A Preparation method of sodium valproate process impurity 2-methyl valeric acid 湖南省湘中制药有限公司 2023-10-10 CN claimed
US-20220128556-A1 METHODS OF DIAGNOSING DISEASE 4D Pharma Cork Limited (IE) 2022-04-28 US claimed
EP-3947743-A1 METHODS OF DIAGNOSING DISEASE 4D Pharma Cork Limited (IE) 2022-02-09 EP claimed
WO-2020201457-A1 METHODS OF DIAGNOSING DISEASE 4D Pharma Cork Limited (IE) 2020-10-08 WO claimed
US-20200147016-A1 METHODS OF MODULATION OF BRANCHED CHAIN ACIDS AND USES THEREOF ACER THERAPEUTICS INC. 2020-05-14 US claimed
CN-106054523-B A kind of degradable photoresist of double-response type and preparation method thereof and application method 北京化工大学 2019-10-18 CN claimed
CN-109851633-A A kind of preparation method of apoester intermediate 肇庆巨元生化有限公司 2019-06-07 CN claimed
WO-2011011781-A1 METHODS OF MODULATION OF BRANCHED CHAIN ACIDS AND USES THEREOF BAYLOR COLLEGE OF MEDICINE (US) 2011-01-27 WO claimed
CN-1980890-A Process for the preparation of atorvastatin RANBAXY LAB LTD (IN) 2007-06-13 CN claimed
EP-1095928-B1 Direct fluorination process for preparing high purity alpha-fluoro-beta-dicarbonyl compounds AIR PROD & CHEM (US) 2004-02-04 EP claimed
EP-1174415-B1 High purity preparation of fluorinated 1,3-dicarbonyls using BDM (bis-fluoroxydifluoromethane) AIR PROD & CHEM (US) 2003-10-22 EP claimed
US-6455728-B1 REACTING METHYL-3-OXOPENTANOATE WTIH HYDROGEN FLUORIDE IN PRESENCE OF OXYGEN; BY-PRODUCT INHIBITION; CHEMICAL INTERMEDIATES FOR PRODUCING PHARMACEUTICALS AIR PRODUCTS AND CHEMICALS, INC. 2002-09-24 US claimed
EP-0912467-B1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE SA (FR) 2002-04-24 EP claimed
EP-1174415-A1 High purity preparation of fluorinated 1,3-dicarbonyls using BDM (bis-fluoroxydifluoromethane) AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-01-23 EP claimed
US-6307105-B1 ELECTROPHILICALLY FLUORINATING A BETA-DICARBONYL WITH BIS(FLUOROXY)DIFLUOROMETHANE IN THE PRESENCE OF AN ACID AIR PRODUCTS AND CHEMICALS, INC. 2001-10-23 US claimed
WO-2001068085-A1 A METHOD FOR STIMULATION OF DEFENSIN PRODUCTION GENAERA CORPORATION (US) 2001-09-20 WO claimed
EP-1095928-A2 Direct fluorination process for preparing high purity alpha-fluoro-beta-dicarbonyl compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 2001-05-02 EP claimed