Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11242418 | 0.85 | FFAR3 (0.38) | TSHRCES2CES1ALDH1A1CYP1A2 | |
| SCHEMBL9315437 | 0.81 | — | — | |
| SCHEMBL166454 | 0.81 | — | — | |
| Toluene SCHEMBL1650313 | 0.77 | LMNA (0.58) | TSHRLMNAALOX12ACHEMEN1 | |
| Toluene SCHEMBL27819683 | 0.77 | LMNA (0.58) | TSHRLMNAALOX12ACHEMEN1 | |
| Toluene SCHEMBL27527983 | 0.77 | LMNA (0.58) | TSHRLMNAALOX12ACHEMEN1 | |
| Toluene SCHEMBL27592105 | 0.77 | LMNA (0.58) | TSHRLMNAALOX12ACHEMEN1 | |
| Toluene SCHEMBL27828012 | 0.76 | LMNA (0.46) | TSHRLMNAALOX12ACHEMEN1 | |
| Toluene SCHEMBL9715675 | 0.76 | LMNA (0.46) | TSHRLMNAALOX12ACHEMEN1 | |
| Toluene SCHEMBL10706293 | 0.74 | LMNA (0.55) | TSHRLMNAALOX12ACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047438-B1 | A PROCESS FOR THE ISOLATION, RECOVERY AND PURIFICATION OF NON-POLAR EXTRACTIVES | CA MINISTER AGRICULTURE & FOOD (CA) | 2004-09-08 | — | — | EP | disclosed |
| US-6495140-B1 | SOLVENT EXTRACTION OF SYNTHETIC AND PLANT EXTRACTS, SEPARATING USING POLYSACCHARIDE GEL MATRICES, THEN REGENERATING THE GELS BY WASHING FOR REUSE | HER MAJESTY IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF AGRICULTURE AND AGRI-FOOD CANADA (CA) | 2002-12-17 | — | — | US | disclosed |
| EP-0109231-B1 | SORBINIL BY OPTICAL RESOLUTION WITH AMINOPINANE DERIVATIVES | PFIZER INC. (US) | 1986-10-22 | — | — | EP | disclosed |
| EP-0109232-B1 | SORBINAL BY OPTICAL RESOLUTION OF PRECURSOR 6-FLURO-4-UREIDOCHROMAN-4-CARBOXYLIC ACID | PFIZER INC. (US) | 1986-10-22 | — | — | EP | disclosed |
| EP-0111387-B1 | REGENERATION OF 6-FLUORO-4-CHROMANONE FROM BY-PRODUCTS IN THE SYNTHESIS OF SORBINIL | PFIZER INC. (US) | 1986-04-09 | — | — | EP | disclosed |
| US-4528387-A | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid | PFIZER INC. (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0111387-A1 | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil | PFIZER INC. (US) | 1984-06-20 | — | — | EP | disclosed |
| EP-0109232-A1 | Sorbinal by optical resolution of precursor 6-fluro-4-ureidochroman-4-carboxylic acid | PFIZER INC. (US) | 1984-05-23 | — | — | EP | disclosed |
| US-4435578-A | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid | PFIZER INC. (US) | 1984-03-06 | — | — | US | disclosed |
| US-4431828-A | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil | PFIZER INC. (US) | 1984-02-14 | — | — | US | disclosed |