Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 9/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773284 | 0.95 | MAOB (0.48) | MAOBMAPK10MAPK8MAPK13MAPK12 | |
| SCHEMBL1664619 | 0.95 | MAOB (0.48) | MAOBMAPK10MAPK8MAPK13MAPK12 | |
| SCHEMBL1666867 | 0.94 | MAPK10 (0.44) | MAOBMAPK10MAPK8MAPK13MAPK12 | |
| SCHEMBL1665065 | 0.92 | MAOB (0.47) | MAOBMAPK10MAPK8MAPK13MAPK12 | |
| SCHEMBL1666869 | 0.89 | MAOB (0.44) | MAOBMAPK10MAPK8MAPK13MAPK12 | |
| SCHEMBL1666178 | 0.89 | MAPK10 (0.41) | MAPK10MAPK8MAPK13MAPK12MAPK11 | |
| SCHEMBL1663566 | 0.89 | MAOB (0.53) | MAOBRAB9ANPC1TNIKCHRNA7 | |
| SCHEMBL1664646 | 0.87 | MAOB (0.48) | MAOBRAB9ANPC1TNIKCHRNA7 | |
| SCHEMBL1665219 | 0.85 | MAPK10 (0.43) | MAOBMAPK10MAPK8MAPK13MAPK12 | |
| SCHEMBL1667299 | 0.85 | HPGDS (0.52) | MAPK10MAPK8MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |