SCHEMBL16647418 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	ADORA3	P0DMS8	1/20	0.46

▸	HPGD	P15428	1/20	0.40

▸	TK1	P04183	2/20	0.39

▸	HINT1	P49773	1/20	0.39

▸	USP2	O75604	1/20	0.39

▸	PNP	P00491	1/20	0.39

▸	TSHR	P16473	1/20	0.39

▸	EDNRA	P25101	1/20	0.39

▸	HTR2A	P28223	1/20	0.39

▸	RECQL	P46063	1/20	0.39

▸	BLM	P54132	1/20	0.39

▸	HBB	P68871	1/20	0.39

▸	HSD17B10	Q99714	1/20	0.39

▸	HPRT1	P00492	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15837491	0.90	ADORA3 (0.46)	ADORA3HPGDTK1HINT1USP2
SCHEMBL16647452	0.89	ADORA3 (0.46)	ADORA3HPGDTK1HINT1USP2
SCHEMBL25524860	0.88	ADORA3 (0.49)	ADORA3HPGDTK1HINT1USP2
SCHEMBL15833027	0.83	ADORA3 (0.49)	ADORA3TK1HINT1USP2PNP
SCHEMBL16374044	0.83	ADORA3 (0.49)	ADORA3TK1HINT1USP2PNP
SCHEMBL16374041	0.83	ADORA3 (0.46)	ADORA3HPGDTK1USP2PNP
SCHEMBL16644431	0.83	ADORA3 (0.46)	ADORA3HPGDTK1USP2PNP
SCHEMBL15833211	0.83	ADORA3 (0.48)	ADORA3TK1HINT1USP2PNP
SCHEMBL15833130	0.83	ADORA3 (0.48)	ADORA3TK1HINT1USP2PNP
SCHEMBL16368147	0.83	ADORA3 (0.46)	ADORA3HPGDTK1USP2PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2015054465-A1	SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF	ALIOS BIOPHARMA, INC. (US)	2015-04-16	—	—	WO	disclosed