Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032286 | 0.90 | IDO1 (0.50) | IDO1NPSR1MALT1DRD2BCHE | |
| SCHEMBL29455260 | 0.89 | CYP3A4 (0.47) | IDO1MAOAMAOBTDP1NPSR1 | |
| SCHEMBL16647700 | 0.87 | CYP3A4 (0.48) | IDO1TDP1NPSR1MALT1DRD2 | |
| SCHEMBL19265866 | 0.85 | IDO1 (0.54) | IDO1MALT1BCHEKIF11MEN1 | |
| SCHEMBL17502351 | 0.81 | KIF11 (0.41) | DRD2BCHEKIF11MEN1KMT2A | |
| SCHEMBL98808 | 0.79 | KIF11 (0.53) | MAOAKIF11 | |
| SCHEMBL3122769 | 0.78 | MALT1 (0.44) | IDO1MAOAMAOBTDP1NPSR1 | |
| SCHEMBL26387246 | 0.78 | SIGMAR1 (0.56) | IDO1MAOAMAOBNPSR1 | |
| SCHEMBL3121407 | 0.77 | MALT1 (0.48) | IDO1MAOAMAOBTDP1MALT1 | |
| SCHEMBL9091074 | 0.77 | KIF11 (0.57) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052155-A1 | PROTECTING GROUP COMPRISING A PURIFICATION TAG | ASCENDIS PHARMA A/S (DK) | 2015-04-16 | — | — | WO | disclosed |