Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 13/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664843 | 0.93 | HPGDS (0.60) | HPGDSRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL1663295 | 0.90 | HPGDS (0.63) | HPGDSRAB9ANPC1KMT2AMAPT | |
| SCHEMBL1664351 | 0.89 | HPGDS (0.62) | HPGDSRAB9ANPC1KMT2AMAPT | |
| SCHEMBL1666278 | 0.87 | HPGDS (0.60) | HPGDSRAB9ANPC1 | |
| SCHEMBL1664868 | 0.84 | HPGDS (0.57) | HPGDSRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL1666281 | 0.84 | HPGDS (0.56) | HPGDSRAB9ANPC1KMT2AMAPT | |
| SCHEMBL1663363 | 0.84 | HPGDS (0.56) | HPGDSRAB9AALDH1A1 | |
| SCHEMBL1664362 | 0.84 | HPGDS (0.56) | HPGDSRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL1664354 | 0.83 | HPGDS (0.63) | HPGDSRAB9ANPC1KMT2AMAPT | |
| SCHEMBL1664676 | 0.83 | HPGDS (0.54) | HPGDSRAB9ANPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |