SCHEMBL16648558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16648422	0.86	LCAT (0.46)	LCATLMNADHFR
	SCHEMBL16648951	0.86	LCAT (0.49)	LCATLMNA
	SCHEMBL16648922	0.85	LCAT (0.48)	LCATCHRM4KDM4EDHFR
	SCHEMBL16648480	0.84	KDM4E (0.54)	LCATKDM4EABL1LMNADGAT1
	SCHEMBL16648511	0.83	LCAT (0.49)	LCAT
	SCHEMBL16648748	0.82	LCAT (0.45)	LCATKDM4EABL1LMNADGAT1
	SCHEMBL16648829	0.81	GPR119 (0.44)	LCATDGAT1DHFR
	SCHEMBL16803678	0.81	KDM4E (0.50)	LCATKDM4EABL1LMNADGAT1
	SCHEMBL16648527	0.80	LCAT (0.44)	LCATLMNADGAT1
	SCHEMBL16648795	0.80	LCAT (0.45)	LCATLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.