SCHEMBL1664873

SCHEMBL1664873

Nc1ccc2ccccc2c1C=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.60
MAPT P10636 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 3/20 0.46
TSHR P16473 2/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
KEAP1 Q14145 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
GAA P10253 1/20 0.46
CYP2A6 P11509 1/20 0.44
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952157 1.00 ERN1 (0.60) ERN1MAPTCYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL2951291 0.98 ERN1 (0.58) ERN1MAPTCYP1A2CYP2C9CYP2C19
Sulfamide SCHEMBL12076368 0.94 ERN1 (0.59) ERN1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL5750570 0.82 ERN1 (0.42) ERN1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL4925725 0.79 IMPDH2 (0.58) ERN1MAPTL3MBTL1RAB9AALDH1A1
SCHEMBL808500 0.78 ERN1 (0.64) ERN1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL29391032 0.78 ERN1 (0.64) ERN1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL5842138 0.78 ERN1 (0.48) ERN1MAPTCYP1A2CYP2C9CYP2C19
Questiomycin B SCHEMBL28194278 0.77 ERN1 (0.77) ERN1MAPTL3MBTL1NPC1RAB9A
SCHEMBL9148679 0.77 ERN1 (0.62) ERN1MAPTCYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3471961-B1 IMPROVED METHOD OF MAKING A FLEXOGRAPHIC PRINTING PLATE MACDERMID GRAPHICS SOLUTIONS LLC (US) 2023-09-20 EP claimed
EP-4185468-A1 IMPROVED METHOD OF MAKING A FLEXOGRAPHIC PRINTING PLATE Macdermid Graphics Solutions, LLC (US) 2023-05-31 EP claimed
US-11602947-B2 Method of making a flexographic printing plate MACDERMID GRAPHICS SOLUTIONS LLC (US) 2023-03-14 US claimed
US-20220024239-A1 Method of Making a Flexographic Printing Plate MACDERMID GRAPHICS SOLUTIONS LLC 2022-01-27 US claimed
EP-3830253-A1 AN OMEGA-TRANSAMINASE ENZYME University College Cork-National University of Ireland Cork (IE) 2021-06-09 EP claimed
EP-3616005-A1 IMPROVED METHOD OF MAKING A FLEXOGRAPHIC PRINTING PLATE Macdermid Graphics Solutions, LLC (US) 2020-03-04 EP claimed
WO-2020025646-A1 AN OMEGA-TRANSAMINASE ENZYME UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) 2020-02-06 WO claimed
EP-3471961-A1 IMPROVED METHOD OF MAKING A FLEXOGRAPHIC PRINTING PLATE Macdermid Graphics Solutions, LLC (US) 2019-04-24 EP claimed
US-10241401-B2 Method of making a flexographic printing plate MACDERMID GRAPHICS SOLUTIONS LLC (US) 2019-03-26 US claimed
CN-109473684-A The elctro-catalyst and preparation method of a kind of sulphur-nitrogen-carbon-based oxygen reduction of transition metal codope and application 中国科学院山西煤炭化学研究所 2019-03-15 CN claimed
US-20180314157-A1 Method of Making A Flexographic Printing Plate MACDERMID GRAPHICS SOLUTIONS, LLC 2018-11-01 US claimed
CN-108129597-A A kind of preparation method of trimesic acid sorbing material 孝感市锐思新材科技有限公司 2018-06-08 CN claimed
US-20180031973-A1 Method of Making a Flexographic Printing Plate MACDERMID GRAPHICS SOLUTIONS, LLC 2018-02-01 US claimed
CN-101037423-A High spermidine conjugates, preparation and application thereof UNIV HENAN (CN) 2007-09-19 CN claimed
US-7268108-B2 Alpha-melanocyte stimulating hormone derivatives and cosmetic application thereof INSTITUT EUROPEAN DE BIOLOGIE CELLULAIRE (FR) 2007-09-11 US claimed
EP-0341963-A2 Parathyroid hormone antagonists MERCK & CO. INC. (US) 1989-11-15 EP claimed
US-4350603-A Novel tris-azo dyes and liquid crystal compositions made therewith GENERAL ELECTRIC COMPANY (US) 1982-09-21 US claimed
EP-4713477-A1 DETECTION OF TARGET ANALYTES USING MULTIMODAL SIGNAL PROBES Roche Molecular Systems, Inc. (US) 2026-03-25 EP disclosed
US-4131064-A Tagging particles which are easily detected by luminescent response, or magnetic pickup, or both WESTINGHOUSE ELECTRIC CORP. (US) 1978-12-26 US disclosed
US-4116644-A CARBURETOR DETERGENT JACKISCH PHILIP F 1978-09-26 US disclosed