Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.35 |
| ▸ | BID | P55957 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662930 | 0.74 | KDM4E (0.36) | POLBF2PLAUELANE | |
| SCHEMBL1664125 | 0.71 | ELANE (0.33) | POLBF2PLAUELANE | |
| SCHEMBL1664651 | 0.68 | ALDH1A1 (0.44) | POLBF2PLAUELANE | |
| SCHEMBL28197780 | 0.64 | PLK1 (0.50) | MCL1PLK1PLK3BIDBCL2L1 | |
| SCHEMBL9334443 | 0.64 | FAAH (0.44) | MCL1FAAHPLK1PLK3BID | |
| SCHEMBL27297604 | 0.63 | PLK1 (0.50) | MCL1PLK1PLK3BIDBCL2L1 | |
| SCHEMBL3691646 | 0.62 | KDM4E (0.52) | POLB | |
| SCHEMBL14836221 | 0.62 | KAT8 (0.53) | MCL1PLK1PLK3BIDBCL2L1 | |
| SCHEMBL8757448 | 0.62 | KAT8 (0.53) | MCL1PLK1PLK3BIDBCL2L1 | |
| SCHEMBL27944035 | 0.62 | KAT8 (0.53) | MCL1PLK1PLK3BIDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |