Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29572058 | 1.00 | TAS1R3 (0.48) | TAS1R3TAS1R1KDM1APDE2ALMNA | |
| SCHEMBL13075501 | 0.87 | KDM1A (0.41) | TAS1R3TAS1R1KDM1APDE2ALMNA | |
| SCHEMBL16649931 | 0.87 | KDM1A (0.41) | TAS1R3TAS1R1KDM1APDE2ALMNA | |
| Hydrochloric Acid SCHEMBL15518191 | 0.85 | KDM1A (0.41) | TAS1R3TAS1R1KDM1APDE2ALMNA | |
| Hydrochloric Acid SCHEMBL15511619 | 0.85 | KDM1A (0.41) | TAS1R3TAS1R1KDM1APDE2ALMNA | |
| SCHEMBL13981506 | 0.85 | ACHE (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL28103261 | 0.85 | ACHE (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL22350128 | 0.83 | TAS1R3 (0.50) | TAS1R3TAS1R1KDM1ALMNAMAPK1 | |
| SCHEMBL20969630 | 0.83 | KDM1A (0.41) | TAS1R3TAS1R1KDM1APDE2ALMNA | |
| SCHEMBL20729406 | 0.82 | TAS1R3 (0.49) | TAS1R3TAS1R1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681215-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2015-04-22 | — | — | EP | claimed |