SCHEMBL16650356

SCHEMBL16650356

C=C(C)C(=O)OCCCC(O)C[Si](OC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
THRB P10828 1/20 0.40
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.33
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27995212 0.81 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8965903 0.79 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1133357 0.79 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28049824 0.79 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL275389 0.79 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL20335177 0.78 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29137093 0.78 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27797460 0.78 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4528593 0.78 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1759348 0.78 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150108388-A1 Light Absorbing Composition And Light-Absorbing Structure Made Therefrom TAIFLEX SCIENTIFIC CO., LTD. (TW) 2015-04-23 US disclosed