Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | FOS | P01100 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16650230 | 0.84 | PARK7 (0.42) | PARK7 | |
| SCHEMBL353845 | 0.83 | PARK7 (0.50) | PARK7KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL16649887 | 0.78 | PARK7 (0.38) | PARK7ALDH1A1NFKB1GAAMAPT | |
| SCHEMBL16650003 | 0.75 | PARK7 (0.43) | PARK7 | |
| SCHEMBL16649823 | 0.71 | PARK7 (0.48) | PARK7ALDH1A1TSHRMAPT | |
| SCHEMBL1286225 | 0.65 | PARK7 (0.52) | PARK7KMT2AMEN1LMNAALDH1A1 | |
| Dehydroxymethylepoxyquinomicin SCHEMBL1669417 | 0.65 | PARK7 (0.54) | PARK7KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL5285137 | 0.64 | ALDH1A1 (0.54) | KMT2AMEN1LMNAALDH1A1FOS | |
| SCHEMBL353155 | 0.63 | PARK7 (0.48) | PARK7JUNNFKB1NFKB2RELA | |
| SCHEMBL25277671 | 0.62 | KMT2A (0.68) | KMT2AMEN1ALDH1A1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411376-B1 | INHIBITORS OF NF-KB | PROFECTUS BIOSCIENCES INC (US) | 2015-04-22 | — | — | EP | claimed |