Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664866 | 0.85 | CNR2 (0.40) | CTSLMETCNR2ADORA2ASMN1; SMN2 | |
| SCHEMBL5056987 | 0.84 | CNR2 (0.42) | CTSLMETHPGDCNR2ADORA2A | |
| SCHEMBL5134079 | 0.83 | HPGD (0.39) | HPGDCNR2ADORA2ASMN1; SMN2CYP11B2 | |
| SCHEMBL6950512 | 0.82 | HPGD (0.41) | CTSLHPGDCNR2SMN1; SMN2CYP11B1 | |
| SCHEMBL6949006 | 0.77 | SMN1; SMN2 (0.40) | HPGDCNR2SMN1; SMN2HTT | |
| SCHEMBL6952421 | 0.77 | NR3C1 (0.42) | METHPGDCNR2SMN1; SMN2CYP11B2 | |
| SCHEMBL1667346 | 0.77 | CNR2 (0.41) | METHPGDCNR2SMN1; SMN2CYP11B2 | |
| SCHEMBL1667873 | 0.72 | PDE10A (0.41) | SMN1; SMN2 | |
| SCHEMBL5056015 | 0.71 | CNR2 (0.45) | CTSLHPGDCNR2ADORA2APDGFRA | |
| SCHEMBL1269677 | 0.67 | DRD4 (0.54) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308867-A2 | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses | UCB Pharma S.A. (BE) | 2011-04-13 | — | — | EP | disclosed |
| EP-2308870-A2 | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses | UCB Pharma S.A. (BE) | 2011-04-13 | — | — | EP | disclosed |