Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ENPP3 | O14638 | 6/20 | 0.59 |
| ▸ | ENPP1 | P22413 | 6/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ABL2 | P42684 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413479 | 0.91 | MEN1 (0.55) | TDP1ENPP3ENPP1ENPP2MEN1 | |
| SCHEMBL11964254 | 0.86 | MEN1 (0.67) | TDP1ENPP3ENPP1ENPP2MEN1 | |
| SCHEMBL27862315 | 0.84 | MEN1 (0.65) | TDP1ENPP3ENPP1ENPP2MEN1 | |
| SCHEMBL1665319 | 0.83 | ENPP1 (0.61) | ENPP3ENPP1ENPP2MEN1KMT2A | |
| SCHEMBL687294 | 0.83 | KMT2A (0.72) | TDP1ENPP3ENPP1ENPP2MEN1 | |
| SCHEMBL1665974 | 0.80 | SMN1; SMN2 (0.68) | TDP1ENPP3ENPP1ENPP2MEN1 | |
| SCHEMBL19146 | 0.79 | TDP1 (0.73) | TDP1ENPP3ENPP1ENPP2KMT2A | |
| SCHEMBL7981247 | 0.79 | TDP1 (0.73) | TDP1ENPP3ENPP1ENPP2KMT2A | |
| SCHEMBL2291594 | 0.79 | TDP1 (0.54) | TDP1ENPP3ENPP1ENPP2MEN1 | |
| SCHEMBL7190628 | 0.79 | MEN1 (0.67) | TDP1ENPP3ENPP1ENPP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314581-B1 | A process for preparing benzo[b]thiophene derivatives | HEXAL AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2322519-A1 | A process for preparing benzo[b]thiophene derivatives | Hexal AG (DE) | 2011-05-18 | — | — | EP | disclosed |
| WO-2011047878-A2 | A PROCESS FOR PREPARING BENZO[B]THIOPHENE DERIVATIVES | HEXAL AKTIENGESELLSCHAFT (DE) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011047877-A1 | A PROCESS FOR PREPARING BENZO[B]THIOPHENE DERIVATIVES | HEXAL AKTIENGESELLSCHAFT (DE) | 2011-04-28 | — | — | WO | disclosed |
| EP-2314581-A1 | A process for preparing benzo[b]thiophene derivatives | Hexal AG (DE) | 2011-04-27 | — | — | EP | disclosed |