Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 5/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.61 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413479 | 0.92 | MEN1 (0.55) | ENPP1ENPP2ENPP3KMT2AMEN1 | |
| SCHEMBL4325565 | 0.85 | KMT2A (0.70) | ENPP1ENPP2ENPP3KMT2AMEN1 | |
| SCHEMBL1665713 | 0.85 | MEN1 (0.70) | ENPP1ENPP2ENPP3KMT2AMEN1 | |
| SCHEMBL18179825 | 0.84 | MEN1 (0.60) | ENPP1ENPP2ENPP3KMT2AMEN1 | |
| SCHEMBL4126086 | 0.84 | MEN1 (0.60) | ENPP1ENPP2ENPP3KMT2AMEN1 | |
| SCHEMBL9852204 | 0.84 | MEN1 (0.60) | ENPP1ENPP2ENPP3KMT2AMEN1 | |
| SCHEMBL1665211 | 0.83 | TDP1 (0.64) | ENPP1ENPP2ENPP3KMT2AMEN1 | |
| SCHEMBL6069317 | 0.83 | ALDH1A1 (0.70) | ENPP1ENPP2ENPP3KMT2AMEN1 | |
| Iodide SCHEMBL22068772 | 0.82 | CA2 (0.59) | ENPP1ENPP2ENPP3KMT2AMEN1 | |
| SCHEMBL27472523 | 0.81 | ALDH1A1 (0.59) | ENPP1ENPP2ENPP3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314581-B1 | A process for preparing benzo[b]thiophene derivatives | HEXAL AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2322519-A1 | A process for preparing benzo[b]thiophene derivatives | Hexal AG (DE) | 2011-05-18 | — | — | EP | disclosed |
| WO-2011047878-A2 | A PROCESS FOR PREPARING BENZO[B]THIOPHENE DERIVATIVES | HEXAL AKTIENGESELLSCHAFT (DE) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011047877-A1 | A PROCESS FOR PREPARING BENZO[B]THIOPHENE DERIVATIVES | HEXAL AKTIENGESELLSCHAFT (DE) | 2011-04-28 | — | — | WO | disclosed |
| EP-2314581-A1 | A process for preparing benzo[b]thiophene derivatives | Hexal AG (DE) | 2011-04-27 | — | — | EP | disclosed |
| US-4520026-A | ANTIARRHYTHMIA AGENTS | S. A. LABAZ N.V. (BE) | 1985-05-28 | — | — | US | disclosed |
| US-4378362-A | CARDIOVASCULAR DISORDERS | S.A. LABAZ N.V. (BE) | 1983-03-29 | — | — | US | disclosed |
| US-4103012-A | CARDIOVASCULAR DISORDERS | LABAZ (FR) | 1978-07-25 | — | — | US | disclosed |