SCHEMBL687294

SCHEMBL687294

CC(=O)c1ccc(OS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.72
MEN1 O00255 1/20 0.72
TDP1 Q9NUW8 2/20 0.59
STS P08842 1/20 0.59
ENPP3 O14638 5/20 0.56
ENPP1 P22413 5/20 0.56
ENPP2 Q13822 3/20 0.55
SMN1; SMN2 Q16637 4/20 0.51
ALDH1A1 P00352 2/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 5/20 0.50
RAB9A P51151 2/20 0.50
MAOB P27338 1/20 0.50
HPGD P15428 1/20 0.50
NPC1 O15118 1/20 0.50
ADAMTS4 O75173 1/20 0.49
CA12 O43570 2/20 0.49
CA9 Q16790 2/20 0.49
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28490431 0.93 KMT2A (0.72) KMT2AMEN1TDP1STSENPP3
SCHEMBL4321339 0.91 MEN1 (0.83) KMT2AMEN1TDP1STSENPP3
SCHEMBL11964254 0.86 MEN1 (0.67) KMT2AMEN1TDP1STSENPP3
SCHEMBL4325565 0.85 KMT2A (0.70) KMT2AMEN1STSENPP3ENPP1
SCHEMBL27862315 0.84 MEN1 (0.65) KMT2AMEN1TDP1STSENPP3
SCHEMBL4321286 0.83 MEN1 (0.68) KMT2AMEN1STSENPP3ENPP1
SCHEMBL1665974 0.83 SMN1; SMN2 (0.68) KMT2AMEN1TDP1STSENPP3
SCHEMBL11569813 0.83 MEN1 (0.68) KMT2AMEN1TDP1STSENPP3
SCHEMBL1665211 0.83 TDP1 (0.64) KMT2AMEN1TDP1STSENPP3
SCHEMBL13578628 0.80 MEN1 (0.63) KMT2AMEN1STSENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 US disclosed
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 US disclosed
EP-1606248-B1 SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DOMPE SPA (IT) 2012-02-29 EP disclosed
US-7737139-B2 Sulfonic acids, their derivatives and pharmaceutical compositions containing them DOMPE PHA.R.MA S.P.A. (IT) 2010-06-15 US disclosed
US-20060258730-A1 Sulfonic acids, their derivatives and pharmaceutical compositions containing them DOMPE S.P.A. (IT) 2006-11-16 US disclosed
EP-1606248-A2 SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dompé S.P.A. (IT) 2005-12-21 EP disclosed
WO-2004080951-A2 SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DOMPE S.P.A. (IT) 2004-09-23 WO disclosed
EP-1457485-A1 Sulfonic acids, their derivatives and pharmaceutical compositions containing them Dompé S.P.A. (IT) 2004-09-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR AFF1, AFF2, FTO KMT2A 314/4885MEN1 1845/4885TDP1 2676/4885
US-20060258730-A1 Sulfonic acids, their derivatives and pharmaceutical compositions containing them CCR8, CCR1, CXCR1 KMT2A 4846/4885MEN1 4816/4885TDP1 3061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.