SCHEMBL16652332

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16662387	0.86	POLB (0.48)	TAAR1ALDH1A1CYP1A2HSD17B10CYP3A4
	SCHEMBL16652723	0.84	TAAR1 (0.64)	TAAR1ALDH1A1CYP1A2HSD17B10CYP3A4
	SCHEMBL712846	0.79	TAAR1 (1.00)	TAAR1ALDH1A1CYP1A2HSD17B10CYP3A4
	Hydrochloric Acid SCHEMBL16651432	0.77	TAAR1 (0.97)	TAAR1ALDH1A1CYP1A2HSD17B10CYP3A4
	Hydrochloric Acid SCHEMBL16651431	0.76	TAAR1 (0.94)	TAAR1ALDH1A1CYP1A2HSD17B10CYP3A4
	SCHEMBL18583898	0.76	TAAR1 (0.53)	TAAR1ALDH1A1CYP1A2HSD17B10CYP3A4
	SCHEMBL16652233	0.75	ACHE (0.60)	ACHE
	SCHEMBL28839913	0.74	TAAR1 (0.53)	TAAR1HTR6
	SCHEMBL9486237	0.74	ALDH1A1 (0.54)	TAAR1ALDH1A1CYP1A2HSD17B10CYP3A4
	SCHEMBL11827175	0.73	TAAR1 (0.47)	TAAR1ALDH1A1CYP1A2HSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.