SCHEMBL16653286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16652927	0.90	KDM4E (0.42)	CYP3A4MAPTKDM4EALDH1A1MEN1
	SCHEMBL16652998	0.88	CYP3A4 (0.38)	CYP3A4MAPTKDM4EALDH1A1MEN1
	SCHEMBL21182481	0.85	KDM4E (0.47)	CYP3A4MAPTKDM4EALDH1A1MEN1
	SCHEMBL13048914	0.83	MAPT (0.45)	CYP3A4MAPTKDM4EALDH1A1HSD17B10
	SCHEMBL16652414	0.83	CYP3A4 (0.39)	CYP3A4MAPTKDM4EALDH1A1MEN1
	SCHEMBL17589807	0.83	KDM4E (0.51)	CYP3A4MAPTKDM4EALDH1A1MEN1
	SCHEMBL16653370	0.82	KDM4E (0.38)	CYP3A4MAPTKDM4EALDH1A1MEN1
	SCHEMBL16653522	0.81	CYP1A2 (0.38)	CYP3A4MAPTKDM4EALDH1A1MEN1
	SCHEMBL16652858	0.81	CYP3A4 (0.39)	CYP3A4MAPTKDM4EALDH1A1MEN1
	SCHEMBL16661890	0.81	RAB9A (0.42)	CYP3A4KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.