SCHEMBL1665386

SCHEMBL1665386

Fc1cc(F)c(F)c(CBr)c1F

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA4 P22748 2/20 0.33
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL9652272 0.92 CA1 (0.34) CA1CA2CA4CA12CA7
SCHEMBL28928458 0.85
SCHEMBL10892912 0.83 CA1 (0.31) CA1CA2CA4CA12CA7
SCHEMBL8575275 0.83 RAPGEF4 (0.32)
SCHEMBL27916218 0.78 CA1 (0.31) CA1CA2CA4CA12CA7
SCHEMBL1584401 0.77
SCHEMBL322232 0.74 CES2 (0.32) CES2CES1
SCHEMBL31103976 0.74 CES2 (0.32) CES2CES1
SCHEMBL28911847 0.74
SCHEMBL578142 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025016469-A1 ALKOXY THIOPHENE ACYL ARYLAMINE COMPOUNDS AND USE THEREOF 复旦大学 2025-01-23 WO disclosed
CN-119320385-A Alkoxy thiophene carboxamide compounds and application thereof 复旦大学 2025-01-17 CN disclosed
CN-118063504-A Fluoro phenyl phosphate compound, perovskite thin film, perovskite solar cell, preparation method, electric equipment and application 天合光能股份有限公司 2024-05-24 CN disclosed
EP-3489569-B1 GAS SUPPLY APPARATUS AND GAS SUPPLY METHOD SHOWA DENKO KK (JP) 2023-01-18 EP disclosed
US-11427907-B2 Gas supply apparatus and gas supply method SHOWA DENKO K.K. (JP) 2022-08-30 US disclosed
US-20220251703-A1 GAS SUPPLY APPARATUS AND GAS SUPPLY METHOD SHOWA DENKO K.K. (JP) 2022-08-11 US disclosed
CN-114716857-A Blue-light-proof hardening liquid and preparation method thereof 丹阳市精通眼镜技术创新服务中心有限公司 2022-07-08 CN disclosed
CN-114605379-A Self-initiation reaction type blue light-proof monomer and preparation method thereof 丹阳市精通眼镜技术创新服务中心有限公司 2022-06-10 CN disclosed
CN-113677729-A Epoxy resin, resin composition, resin sheet, cured resin, resin substrate, and laminated substrate TDK株式会社 2021-11-19 CN disclosed
CN-109477613-B Gas supply device and gas supply method 昭和电工株式会社 2021-11-19 CN disclosed
US-20090025781-A1 NOVEL AMINO GROUP-CONTAINING HETEROCYCLIC DERIVATIVES AND SENSITIZING DYES FOR PHOTOELECTRIC CONVERSION CONTAINING THE HETEROCYCLIC DERIVATIVES AGC SEIMI CHEMICAL CO., LTD. (JP) 2009-01-29 US disclosed
US-20080318928-A1 BENGAMIDES WITH A SUBSTITUTED CAPROLACTAM CYCLE, METHOD FOR THE PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF AVENTIS PHARMA S.A. (FR) 2008-12-25 US disclosed
US-7456169-B2 Heterocyclic kinase inhibitors ABBOTT LABORATORIES INC. (US) 2008-11-25 US disclosed
US-20070254867-A1 Heterocyclic Kinase Inhibitors ABBVIE INC. 2007-11-01 US disclosed
US-20070249584-A1 BENGAMIDES WITH A SUBSTITUTED CAPROLACTAME CYCLE, METHOD FOR THE PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF AVENTIS PHARMA S.A. (FR) 2007-10-25 US disclosed
US-4868209-A AGRICULTURAL INSECTICIDES, CYCLOPROPANE CARBOXYLIC ACIDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-09-19 US disclosed
EP-0054360-B1 FLUOROBENZYL CYCLOPROPANE CARBOXYLATES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE AS INSECTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-06-05 EP disclosed
US-4370346-A INSECTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-01-25 US disclosed
EP-0060617-A1 Fluorobenzyl cyclopropane carboxylates, their preparation, compositions and use as insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-22 EP disclosed
EP-0054360-A2 Fluorobenzyl cyclopropane carboxylates, their preparation, compositions comprising them and their use as insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-06-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249584-A1 BENGAMIDES WITH A SUBSTITUTED CAPROLACTAME CYCLE, METHOD FOR THE PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF CDK4, CCNI, RCE1 CA1 3093/4885CA2 3444/4885CA4 1601/4885
US-20080318928-A1 BENGAMIDES WITH A SUBSTITUTED CAPROLACTAM CYCLE, METHOD FOR THE PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF CDK4, CCNI, CCNT2 CA1 2822/4885CA2 3292/4885CA4 1386/4885
US-20090025781-A1 NOVEL AMINO GROUP-CONTAINING HETEROCYCLIC DERIVATIVES AND SENSITIZING DYES FOR PHOTOELECTRIC CONVERSION CONTAINING THE HETEROCYCLIC DERIVATIVES HRH3, HRH4, AHR CA1 2733/4885CA2 1325/4885CA4 2327/4885
US-20070254867-A1 Heterocyclic Kinase Inhibitors MAP3K20, MAP3K19, MAP4K2 CA1 4152/4885CA2 3100/4885CA4 4197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.